a-PiHP

a-PiHP (other names: α-PHiP, α-PiHP, 4-Me-pvp, ALPHA.-PHIP, alpha-Pyrrolidinoisohexaphenone, alpha-Pyrrolidinoisohexanophenone) is a substance of the cathinone class, an isomer of pyrovalerone, and has a similar structure and effects.

Chemistry
a-PiHP is an alpha-isobutyl derivative of pyrovalerone. This substance is a positional isomer of pyrovalerone, where the methyl group is shifted from the 4th position of the aromatic ring to the 4th position of the acyl chain.

Pharmacology
a-PiHP is sold online as a drug for recreational use. The substance is not yet well studied and information on toxicological and pharmacological properties is available.
Data from studies in mice showed that a-PiHP has the highest in vitro efficacy as a dopamine transporter inhibitor of alpha-substituted derivatives.

Legal status
CA: Schedule I
Germany: Anlage II, Authorized trade only, not prescription.
UK: Class B controlled substance.
USA: Category I, isomer of a-PHP.

Technical Information:

Product Name: a-PiHP
Other Name(s): α-PHiP, α-PiHP, 4-Me-pvp, ALPHA.-PHIP, alpha-Pyrrolidinoisohexaphenone, alpha-Pyrrolidinoisohexanophenone
IUPAC Name: 4-methyl-1-phenyl-2-pyrrolidin-1-ylpentan-1-one
CAS: 2181620-71-1
Molar Mass: 245.36 g/mol
Molecular Formula: C16H23NO
InChi Code: InChI=1S/C16H23NO/c1-13(2)12-15(17-10-6-7-11-17)16(18)14-8-4-3-5-9-14/h3-5,8-9,13,15H,6-7,10-12H2,1-2H3
InChIKey: UOZWZANRCOALQL-UHFFFAOYSA-N
Canonical SMILES: CC(C)CC(C(=O)C1=CC=CC=C1)N2CCCC2
Formulation: A crystalline solid
NMR a-PiHP