N-Desethylisotonitazene

N-Desethylisotonitazene (Des-Iso) is an opioid substance derived from benzimidazole, an active metabolite of isotonitazene. This substance is a strong agonist of opioid receptors and, in comparison with fentanyl, exceeds it by 20 times.

History
This substance is relatively new, positioned as a design drug for chemical research

Chemistry
N-Desethylisotonitazeneis a metabolite of isotonitazene and has a similar structure.

Pharmacology
Data on the toxicological and pharmacological properties of the substance are incomplete, since the substance is relatively new, all the data presented about this substance are based on studies on mice.
N-Desethylisotonitazene is a strong agonist of opioid receptors and can act as a strong analgesic, causing effects such as relaxing and euphoria characteristic of opioid analgesics.

Legal status
N-Desethylisotonitazene has an unclear legal status, can be sold in many countries as a substance for research and scientific purposes, for use in specially equipped laboratories.
This substance may be banned for sale and use in countries where analogues of isotonitazene are controlled by law.

Technical Information:

Product Name: N-Desethylisotonitazene HCL
Other Name(s): Des-Iso
IUPAC Name: N-ethyl-2-[[4-(1-methylethoxy)phenyl]methyl]-5-nitro-1H-benzimidazole-1-ethanamine
CAS:
“2732926-24-6”
Molar Mass: 418.9
Molecular Formula: C21H26N4O3 • HCl
InChi Code: InChI=1S/C21H26N4O3.ClH/c1-4-22-11-12-24-20-10-7-17(25(26)27)14-19(20)23-21(24)13-16-5-8-18(9-6-16)28-15(2)3;/h5-10,14-15,22H,4,11-13H2,1-3H3;1H
InChIKey: YGIGEJHYUUWLMA-UHFFFAOYSA-N
Canonical SMILES: CCNCCN1C(CC2=CC=C(OC(C)C)C=C2)=NC3=CC([N+]([O-])=O)=CC=C31.Cl
Formulation: A crystalline solid
NMR N-Desethylisotonitazene