N-Desethyletonitazene

N-Desethyletonitazene (NDE, Noretonitazene, N-desethyl Etonitazene) is a benzimidazole derivative opioid substance, a metabolite of etonitazene, with high μ-opioid activity.

History
This substance is comparatively new and is positioned as a designer drug for chemical research.

Chemistry
N-Desethyletonitazene is an active metabolite of etonitazene and has a related structure.

Pharmacology
Data on the toxicological and pharmacological properties of the substance are incomplete, since the substance is relatively new, all the data presented about this substance are based on studies on mice.
N-Desethyletonitazene has high μ-opioid activity and acts as a strong analgesic, causing sedation and ephoria. High doses of the drug may cause side effects such as itching, respiratory depression, and vomiting.

Legal status
N-Desethyletonitazene has an unclear legal status, can be sold in many countries as a substance for research and scientific purposes, for use in specially equipped laboratories.
This substance may be banned for sale and use in countries where analogues of etonitazene are controlled by law.

Technical Information:

Product Name: N-Desethyletonitazene HCL
Other Name(s): NDE, Noretonitazene, N-desethyl Etonitazene
IUPAC Name: 2-[2-[(4-ethoxyphenyl)methyl]-5-nitrobenzimidazol-1-yl]-N-ethylethanamine
CAS: 2732926-26-8
Molar Mass: 368.4 g/mol
Molecular Formula: C20H24N4O3 • HCl
InChi Code: InChI=1S/C20H24N4O3/c1-3-21-11-12-23-19-10-7-16(24(25)26)14-18(19)22-20(23)13-15-5-8-17(9-6-15)27-4-2/h5-10,14,21H,3-4,11-13H2,1-2H3
InChIKey: RESPFUMJVJRUMB-UHFFFAOYSA-N
Canonical SMILES: CCNCCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OCC
Formulation: A crystalline solid
NMR N-Desethyletonitazene