4′-Fluoro-4-methylaminorex (other names: 4F-MAR, 4-FPO, para-fluoro-4-Methylaminorex, p-F-4-Methylaminorex) is a stimulant of the 2-amino-5-aryloxazoline class, a metabolite of aminorex(a stimulant that was first synthesized in 1960 by McNeil Laboratories). 4F-MAR has effects comparable to methamphetamine, but with a longer duration of action.
Chemistry
4-Fluoro-4-methylaminorex is a structural fluorinated metabolite of aminorex.
Pharmacology
4F-MAR is a designer substance whose toxicological and pharmacological properties are not fully understood. All data presented are from observational and chemical studies in mice.
4F-MAR can cause such effects as stimulation, increased attention, cognitive ability, euphoria. The average duration of action is up to 16 hours, at high doses up to 36 hours.
Legal status
Italy: Controlled substance under the law
May not be legal in countries where aminorex analogs are legally controlled.
Technical Information:
Product Name: 4F-MAR
Other Name(s): 4′-Fluoro-4-methylaminorex, 4-FPO, para-fluoro-4-Methylaminorex, p-F-4-Methylaminorex
IUPAC Name: 4-methyl-5-(4-fluorophenyl)-4,5-dihydro-1,3-oxazol-2-amine
5-(4-fluorophenyl)-4-methyl-4,5-dihydrooxazol-2-amine
CAS: 1364933-64-1
Molar Mass: 194.21 g/mol
Molecular Formula: C10H11FN2O
InChi Code: InChI=1S/C10H11FN2O/c1-6-9(14-10(12)13-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H2,12,13)
InChIKey: UYKYWISHPDEDRQ-UHFFFAOYSA-N
Canonical SMILES: CC1C(OC(=N1)N)C2=CC=C(C=C2)F
Formulation: A crystalline solid
NMR 4F-MAR












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